Head Coach: Jeff Walz Record: 27-7 (12-4 ACC)
| Date | Site | Opp AP | Opponent | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/14/2014 | A | IUPUI | W | 89 | 69 | 1-0 | 0-0 | 3,159 | Indianapolis | Ind. | The Coliseum | |||
| 11/16/2014 | H | Tennessee-Martin | W | 77 | 43 | 2-0 | 0-0 | 7,892 | Louisville | Ky. | KFC Yum! Center | |||
| 11/20/2014 | H | Belmont | W | 95 | 35 | 3-0 | 0-0 | 7,404 | Louisville | Ky. | KFC Yum! Center | |||
| 11/23/2014 | H | Ball State | W | 69 | 56 | 4-0 | 0-0 | 8,081 | Louisville | Ky. | KFC Yum! Center | |||
| 11/25/2014 | H | Western Kentucky | W | 89 | 67 | 5-0 | 0-0 | 8,463 | Louisville | Ky. | KFC Yum! Center | |||
| 11/28/2014 | H | Lafayette | W | 102 | 61 | 6-0 | 0-0 | 7,923 | Louisville | Ky. | KFC Yum! Center | |||
| 11/30/2014 | A | Valparaiso | W | 86 | 59 | 7-0 | 0-0 | 567 | Valparaiso | Ind. | Ath. Recreation Center | |||
| 12/04/2014 | H | 22 | Iowa | W | 86 | 52 | 8-0 | 0-0 | 7,854 | Louisville | Ky. | KFC Yum! Center | 2014 ACC/Big Ten Challenge | |
| 12/07/2014 | H | 13 | Kentucky | L | 68 | 77 | 8-1 | 0-0 | 14,862 | Louisville | Ky. | KFC Yum! Center | ||
| 12/15/2014 | H | Old Dominion | W | 100 | 46 | 9-1 | 0-0 | 7,726 | Louisville | Ky. | KFC Yum! Center | |||
| 12/18/2014 | A | Grand Canyon | W | 65 | 51 | 10-1 | 0-0 | 2,049 | Phoenix | Ariz. | Grand Canyon Arena | |||
| 12/21/2014 | A | 24 | California | W | 70 | 57 | 11-1 | 0-0 | 8,339 | Berkeley | Calif. | Haas Pavilion | ||
| 12/29/2014 | H | Evansville | W | 73 | 51 | 12-1 | 0-0 | 7,909 | Louisville | Ky. | KFC Yum! Center | |||
| 01/02/2015 | H | Georgia Tech | W | 75 | 48 | 13-1 | 1-0 | 9,049 | Louisville | Ky. | KFC Yum! Center | |||
| 01/04/2015 | A | Pittsburgh | W | 63 | 57 | 14-1 | 2-0 | 1,811 | Pittsburgh | Pa. | Petersen Events Center | |||
| 01/11/2015 | A | Wake Forest | W | 79 | 68 | 15-1 | 3-0 | 719 | Winston-Salem | N.C. | LJVM Coliseum | |||
| 01/14/2015 | H | North Carolina State | W | 65 | 58 | 16-1 | 4-0 | 7,736 | Louisville | Ky. | KFC Yum! Center | |||
| 01/18/2015 | H | Virginia | W | 67 | 55 | 17-1 | 5-0 | 11,322 | Louisville | Ky. | KFC Yum! Center | |||
| 01/22/2015 | A | 17 | Florida State | L | 63 | 68 | 17-2 | 5-1 | 2,847 | Tallahassee | Fla. | Donald L. Tucker Center | ||
| 01/25/2015 | H | Miami, Fla. | W | 68 | 55 | 18-2 | 6-1 | 9,887 | Louisville | Ky. | KFC Yum! Center | |||
| 01/29/2015 | H | 23 | Syracuse | W | 78 | 58 | 19-2 | 7-1 | 8,387 | Louisville | Ky. | KFC Yum! Center | ||
| 02/02/2015 | A | 15 | Duke | L | 58 | 66 | 19-3 | 7-2 | 5,790 | Durham | N.C. | Cameron Indoor Stadium | ||
| 02/08/2015 | H | Pittsburgh | W | 48 | 35 | 20-3 | 8-2 | 13,656 | Louisville | Ky. | KFC Yum! Center | |||
| 02/12/2015 | A | Clemson | W | 81 | 49 | 21-3 | 9-2 | 1,394 | Clemson | S.C. | Littlejohn Coliseum | |||
| 02/15/2015 | H | 17 | North Carolina | W | 75 | 66 | 22-3 | 10-2 | 13,115 | Louisville | Ky. | KFC Yum! Center | ||
| 02/19/2015 | A | Virginia Tech | W | 69 | 49 | 23-3 | 11-2 | 1,573 | Blacksburg | Va. | Cassell Coliseum | |||
| 02/23/2015 | A | 4 | Notre Dame | L | 52 | 68 | 23-4 | 11-3 | 8,911 | South Bend | Ind. | Purcell Pavilion | ||
| 02/26/2015 | H | Boston College | W | 77 | 60 | 24-4 | 12-3 | 10,488 | Louisville | Ky. | KFC Yum! Center | |||
| 03/01/2015 | A | Virginia | L | 59 | 75 | 24-5 | 12-4 | 3,744 | Charlottesville | Va. | JPJ Arena | |||
| 03/06/2015 | N | 15 | North Carolina | W | 77 | 75 | OT | 25-5 | 12-4 | 5,848 | Greensboro | N.C. | Greensboro Coliseum | 2015 ACC Tournament |
| 03/07/2015 | N | 7 | Florida State | L | 51 | 66 | 25-6 | 12-4 | 7,108 | Greensboro | N.C. | Greensboro Coliseum | 2015 ACC Tournament | |
| 03/21/2015 | N | Brigham Young | W | 86 | 53 | 26-6 | 12-4 | 5,560 | Tampa | Fla. | Sun Dome | 2015 NCAA Tournament First Round | ||
| 03/23/2015 | A | 25 | South Florida | W | 60 | 52 | 27-6 | 12-4 | 5,014 | Tampa | Fla. | Sun Dome | 2015 NCAA Tournament Second Round | |
| 03/28/2015 | N | Dayton | L | 66 | 82 | 27-7 | 12-4 | 8,259 | Albany | N.Y. | Times Union Center | 2015 NCAA Tournament Sweet Sixteen |