Head Coach: Bud Childers Record: 20-9 (11-1 Metro)
| Date | Site | Opponent | W/L | UL | Opp | Overall | Conf | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/29/1991 | N | South Carolina | W | 74 | 47 | 1-0 | 0-0 | 1991 Downeast Women's Basketball Classic | |||
| 11/30/1991 | N | Wisconsin-Green Bay | W | 68 | 62 | 2-0 | 0-0 | 1991 Downeast Women's Basketball Classic | |||
| 12/07/1991 | N | Penn State | L | 75 | 84 | 2-1 | 0-0 | 1991 Lady Buckeye Classic | |||
| 12/08/1991 | N | Boston College | W | 92 | 78 | 3-1 | 0-0 | 1991 Lady Buckeye Classic | |||
| 12/11/1991 | H | Evansville | W | 71 | 67 | 4-1 | 0-0 | Louisville | Ky. | Commonwealth Convention Center | |
| 12/14/1991 | A | Eastern Illinois | W | 69 | 66 | 5-1 | 0-0 | ||||
| 12/19/1991 | H | Oregon | L | 70 | 76 | 5-2 | 0-0 | Louisville | Ky. | Freedom Hall | |
| 12/21/1991 | A | Bradley | L | 67 | 71 | 5-3 | 0-0 | ||||
| 12/28/1991 | H | Hartford | W | 80 | 50 | 6-3 | 0-0 | 1991 Seelbach Cardinal Classic | |||
| 12/29/1991 | H | Texas Tech | L | 53 | 66 | 6-4 | 0-0 | 1991 Seelbach Cardinal Classic | |||
| 01/05/1992 | A | Purdue | L | 52 | 73 | 6-5 | 0-0 | ||||
| 01/13/1992 | H | Northeastern Illinois | W | 96 | 46 | 7-5 | 0-0 | ||||
| 01/15/1992 | A | Notre Dame | W | 64 | 53 | 8-5 | 0-0 | ||||
| 01/18/1992 | H | Southern Mississippi | W | 72 | 67 | 9-5 | 1-0 | ||||
| 01/20/1992 | H | Tulane | W | 66 | 55 | 10-5 | 2-0 | ||||
| 01/25/1992 | H | Virginia Commonwealth | W | 94 | 57 | 11-5 | 3-0 | Louisville | Ky. | Freedom Hall | |
| 01/27/1992 | H | Virginia Tech | W | 93 | 44 | 12-5 | 4-0 | ||||
| 02/02/1992 | H | Western Kentucky | L | 70 | 80 | 12-6 | 4-0 | ||||
| 02/08/1992 | A | South Florida | W | 74 | 70 | 13-6 | 5-0 | ||||
| 02/10/1992 | A | Charlotte | L | 66 | 68 | 13-7 | 5-1 | ||||
| 02/15/1992 | H | Southern Mississippi | W | 98 | 67 | 14-7 | 6-1 | ||||
| 02/19/1992 | A | Kentucky | L | 73 | 81 | 14-8 | 6-1 | ||||
| 02/22/1992 | A | Virginia Commonwealth | W | 91 | 54 | 15-8 | 7-1 | ||||
| 02/24/1992 | A | Virginia Tech | W | 76 | 56 | 16-8 | 8-1 | ||||
| 02/29/1992 | H | South Florida | W | 91 | 86 | 17-8 | 9-1 | ||||
| 03/02/1992 | H | Charlotte | W | 73 | 63 | 18-8 | 10-1 | ||||
| 03/07/1992 | H | Tulane | W | 84 | 64 | 19-8 | 11-1 | Louisville | Ky. | Freedom Hall | |
| 03/12/1992 | H | Virginia Commonwealth | W | 88 | 80 | 20-8 | 11-1 | Louisville | Ky. | Commonwealth Convention Center | 1992 Metro Tournament |
| 03/13/1992 | H | Southern Mississippi | L | 76 | 85 | 20-9 | 11-1 | Louisville | Ky. | Freedom Hall | 1992 Metro Tournament |