Head Coach: Bud Childers Record: 17-12 (7-7 Metro)
| Date | Site | Opponent | W/L | UL | Opp | OT | Overall | Conf | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/25/1989 | A | Northern Kentucky | L | 60 | 71 | 0-1 | 0-0 | |||||
| 11/28/1989 | A | Indiana State | W | 69 | 50 | 1-1 | 0-0 | |||||
| 12/01/1989 | A | Missouri | L | 61 | 72 | 1-2 | 0-0 | 1989 Mid American Classic | ||||
| 12/02/1989 | N | Western Illinois | W | 76 | 56 | 2-2 | 0-0 | 1989 Mid American Classic | ||||
| 12/06/1989 | H | Dayton | W | 60 | 54 | 3-2 | 0-0 | Louisville | Ky. | Freedom Hall | ||
| 12/09/1989 | H | Eastern Kentucky | W | 85 | 84 | OT | 4-2 | 0-0 | Louisville | Ky. | Freedom Hall | |
| 12/13/1989 | A | Marshall | L | 78 | 85 | 4-3 | 0-0 | |||||
| 12/18/1989 | H | Wright State | W | 70 | 50 | 5-3 | 0-0 | Louisville | Ky. | Freedom Hall | ||
| 12/21/1989 | H | Evansville | W | 65 | 41 | 6-3 | 0-0 | Louisville | Ky. | Commonwealth Conv. Center | ||
| 01/04/1990 | H | Detroit Mercy | W | 88 | 74 | 7-3 | 0-0 | Louisville | Ky. | Freedom Hall | ||
| 01/06/1990 | H | Southern Mississippi | W | 82 | 76 | OT | 8-3 | 1-0 | Louisville | Ky. | Manual High School | |
| 01/08/1990 | H | Memphis | W | 85 | 58 | 9-3 | 2-0 | Louisville | Ky. | Manual High School | ||
| 01/13/1990 | A | Florida State | L | 66 | 69 | OT | 9-4 | 2-1 | ||||
| 01/15/1990 | A | South Carolina | L | 52 | 65 | 9-5 | 2-2 | |||||
| 01/20/1990 | A | Morehead State | W | 78 | 71 | OT | 10-5 | 2-2 | ||||
| 01/22/1990 | H | Cincinnati | W | 54 | 50 | 11-5 | 3-2 | Louisville | Ky. | Commonwealth Conv. Center | ||
| 01/27/1990 | A | Tulane | W | 65 | 64 | 12-5 | 4-2 | |||||
| 01/29/1990 | H | Virginia Tech | L | 54 | 65 | 12-6 | 4-3 | Louisville | Ky. | Freedom Hall | ||
| 02/03/1990 | A | Southern Mississippi | L | 58 | 74 | 12-7 | 4-4 | |||||
| 02/05/1990 | A | Memphis | W | 82 | 79 | 13-7 | 5-4 | |||||
| 02/08/1990 | A | Austin Peay | W | 91 | 87 | 14-7 | 5-4 | |||||
| 02/10/1990 | H | Florida State | L | 62 | 77 | 14-8 | 5-5 | Louisville | Ky. | Freedom Hall | ||
| 02/12/1990 | H | South Carolina | L | 64 | 74 | 14-9 | 5-6 | Louisville | Ky. | Commonwealth Conv. Center | ||
| 02/14/1990 | A | Kentucky | L | 68 | 83 | 14-10 | 5-6 | |||||
| 02/19/1990 | H | Tulane | W | 77 | 52 | 15-10 | 6-6 | Louisville | Ky. | Commonwealth Conv. Center | ||
| 02/26/1990 | A | Virginia Tech | L | 62 | 81 | 15-11 | 6-7 | |||||
| 03/03/1990 | A | Cincinnati | W | 74 | 54 | 16-11 | 7-7 | |||||
| 03/08/1990 | N | Virginia Tech | W | 85 | 60 | 17-11 | 7-7 | 1990 Metro Tournament | ||||
| 03/09/1990 | N | South Carolina | L | 60 | 80 | 17-12 | 7-7 | 1990 Metro Tournament |