Head Coach: Peggy Fiehrer Record: 17-14 (4-6 Metro)
| Date | Site | Opponent | W/L | UL | Opp | Overall | Conf | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/25/1984 | A | Western Michigan | W | 93 | 83 | 1-0 | 0-0 | ||||
| 11/28/1984 | H | Northern Kentucky | W | 76 | 61 | 2-0 | 0-0 | Louisville | Ky. | Manual High School | |
| 12/01/1984 | A | Illinois State | L | 57 | 74 | 2-1 | 0-0 | ||||
| 12/03/1984 | H | IUPUI | W | 90 | 63 | 3-1 | 0-0 | Louisville | Ky. | Freedom Hall | |
| 12/05/1984 | H | Bellarmine | W | 80 | 56 | 4-1 | 0-0 | Louisville | Ky. | Manual High School | |
| 12/07/1984 | N | Cheyney | W | 65 | 61 | 5-1 | 0-0 | 1984 No. Illinois Fastbreak Festival | |||
| 12/08/1984 | A | Northern Illinois | W | 68 | 66 | 6-1 | 0-0 | 1984 No. Illinois Fastbreak Festival | |||
| 12/12/1984 | H | Morehead State | W | 68 | 57 | 7-1 | 0-0 | Louisville | Ky. | Manual High School | |
| 12/17/1984 | H | Kentucky State | W | 72 | 53 | 8-1 | 0-0 | Louisville | Ky. | Freedom Hall | |
| 12/19/1984 | A | East Tennessee State | W | 66 | 53 | 9-1 | 0-0 | ||||
| 12/22/1984 | H | Indiana State | W | 87 | 75 | 10-1 | 0-0 | Louisville | Ky. | Manual High School | |
| 01/03/1985 | A | Tulane | W | 84 | 65 | 11-1 | 1-0 | ||||
| 01/05/1985 | A | Southern Mississippi | L | 83 | 93 | 11-2 | 1-1 | ||||
| 01/06/1985 | A | New Orleans | W | 73 | 72 | 12-2 | 1-1 | ||||
| 01/10/1985 | H | Memphis | L | 93 | 99 | 12-3 | 1-2 | ||||
| 01/12/1985 | H | Florida State | W | 89 | 74 | 13-3 | 2-2 | Louisville | Ky. | Manual High School | |
| 01/15/1985 | A | Western Kentucky | L | 66 | 91 | 13-4 | 2-2 | ||||
| 01/19/1985 | H | Kentucky | W | 67 | 63 | 14-4 | 2-2 | Louisville | Ky. | Freedom Hall | |
| 01/21/1985 | A | Alabama | L | 63 | 74 | 14-5 | 2-2 | ||||
| 01/26/1985 | H | South Carolina | L | 72 | 73 | 14-6 | 2-3 | Louisville | Ky. | Freedom Hall | |
| 01/28/1985 | H | Virginia Tech | L | 74 | 79 | 14-7 | 2-4 | Louisville | Ky. | Manual High School | |
| 02/02/1985 | H | Cincinnati | W | 81 | 79 | 15-7 | 3-4 | Louisville | Ky. | Freedom Hall | |
| 02/07/1985 | A | South Carolina | L | 73 | 90 | 15-8 | 3-5 | ||||
| 02/09/1985 | A | Virginia | L | 60 | 74 | 15-9 | 3-5 | ||||
| 02/10/1985 | A | Virginia Tech | W | 70 | 68 | 16-9 | 4-5 | ||||
| 02/16/1985 | A | Cincinnati | L | 70 | 86 | 16-10 | 4-6 | ||||
| 02/18/1985 | H | Vanderbilt | L | 67 | 93 | 16-11 | 4-6 | Louisville | Ky. | Freedom Hall | |
| 02/22/1985 | N | Hawaii | W | 88 | 58 | 17-11 | 4-6 | 1985 Northern Lights Trnmt. | |||
| 02/23/1985 | N | Penn State | L | 69 | 105 | 17-12 | 4-6 | 1985 Northern Lights Trnmt. | |||
| 02/24/1985 | N | North Carolina | L | 71 | 86 | 17-13 | 4-6 | 1985 Northern Lights Trnmt. | |||
| 03/03/1985 | A | Southern Mississippi | L | 64 | 79 | 17-14 | 4-6 | 1985 Metro Tournament |